Weight Loss Information

Getting the right information should be easy. Our FAQs are designed to give you quick, clear answers so you can feel confident and in control of your health journey. Find what you're looking for below throughout your weight loss journey with Zepbound.

About Zepbound / Zepbound Usage

What is Zepbound and how does it work?

Zepbound (tirzepatide) is a once-weekly injection that combines GLP-1 and GIP receptor agonists to support weight loss, regulate blood sugar, and reduce appetite.

How do I inject it?

  • Inject into the abdomen or thigh.
  • Use a new needle every time.
  • Watch our instructional video at gifthealth.com for full guidance.

How often should I inject it?

Follow your healthcare provider’s prescription. Most patients inject once per week.

Can I increase my dose?

Only with approval from your provider. Most dose increases happen in 2.5mg increments. We’ll need a new prescription for changes.

What’s the difference between the vial and auto-injector?

  • Vial: More flexible and cost-effective. Requires syringes.
  • Auto-injector: Easier to use but more expensive. May be insurance-covered.

Prescription & Checkout Process

How do I make sure I get the right medication?

We double-check each order for:

  • Correct strength (e.g., 2.5mg, 5mg)
  • Correct form (vial vs. pen)
  • Matching prescription details

You’ll see your order summary before you pay—review it carefully.

How do I complete checkout?

You’ll receive a secure link via text to finalize payment. If the link expires, click it to request a new one.

What if my checkout link expired?

Click it anyway! You’ll be prompted to request a new one.

How can my doctor send a prescription?

Ask them to e-prescribe to:

LillyDirect Self Pay Pharmacy Solutions

  • NPI: 1689411712
  • NCPDP: 3692539

Prescription, Orders, Shipping & Delivery

Can providers prescribe Zepbound to themselves?

No. Self-prescribing is not accepted and may delay your order. Have another licensed provider submit your prescription.

What if my prescription wasn’t accepted?

Common issues:

  • Missing quantity or unclear directions
  • Not specifying 'vial' formulation

We will notify your provider and await corrections to your prescription.

How can I check if my prescription is on file?

You’ll receive a confirmation text when we receive it. If  you do not, confirm it was sent to: LillyDirect Self Pay Pharmacy Solutions

Can I transfer my prescription to a local pharmacy?

No. Vial prescriptions are only available through Gifthealth under the LillyDirect Self Pay program.

How can I avoid issues with my order?

  • Double-check your prescription details.
  • Confirm your dose matches your doctor’s guidance.
  • If anything looks off during checkout, stop and contact us.

What if my order arrives and it’s incorrect?

Contact Gifthealth right away. We’ll investigate and resolve the issue quickly.

Why was my package returned to sender?

Reasons can include:

  • Incorrect or incomplete shipping address.
  • Missed delivery window for refrigerated items.
  • Weather or shipping delays.

We’ll automatically send a replacement if this happens.

Is my medication safely packaged?

Yes! We use temperature-controlled packaging and URAC-accredited pharmacy practices to ensure safety and quality.

When will my order ship?

  • Monday–Friday only.
  • Weekend/holiday orders ship the next business day.
  • Puerto Rico: Orders ship Mon–Wed only.

How is it shipped?

Via UPS with tracking. You’ll receive a link by text when it ships.

What’s in the box?

  • 4 vials
  • 3–4 ice packs
  • Syringes (not pre-filled)
  • Bubble wrap and insulation

Medication Use & Safety

Can I return my medication?

No. By federal law, prescription medications cannot be returned to a pharmacy for reuse or resale—even if unopened. This protects all patients from potential safety risks.Even sealed medications could have been stored incorrectly or tampered with. To ensure safety and integrity, all medication sales are final.

What if I experience side effects?

  • Contact your healthcare provider immediately for medical advice.
  • Call Gifthealth if you're unsure whether side effects are normal—we’re here to help.
  • Remember: side effects do not make a prescription returnable, but we’ll guide you through next steps.

What if my medication feels warm when it is delivered?

Contact us. We’ll verify the shipping timeline and perform a temperature assessment if needed.

Communication & Support

Why haven’t I heard from Gifthealth?

It may be because we haven’t received your prescription yet. Confirm with your provider and ensure they sent it to:

LillyDirect Self Pay Pharmacy Solutions

  • NPI: 1689411712
  • NCPDP: 3692539

What’s the best way to reach you?

  • Chat: gifthealth.com
  • Phone: (833) 707-6619
  • Virtual Agent: Call and press Option 2 for common questions

Pricing & Self-Pay Program

How much does Zepbound cost?

  • 2.5mg vials: $349/month
  • 5mg to 15mg vials: $499/month

These prices apply if you refill within 45 days of your last delivery. All purchases are cash-only and include 4 vials per 28-day supply.

Are there payment plans or discounts?

  • No payment plans are offered.
  • Injection supply kits are available for $5 at checkout.
  • You may use an HSA or FSA if your insurance allows—check with your provider.

What if I miss the 45-day refill window?

If more than 45 days pass, the self-pay discount expires. The non-discounted prices are:

  • 7.5mg = $599
  • 10mg = $699
  • 12.5mg = $849
  • 15mg = $1,049

Walmart Retail Pickup

How do I choose Walmart pickup instead of home delivery during checkout?

When checking out your Zepbound vial prescription through LillyDirect powered by Gifthealth, you’ll see delivery options.

Select “Local Pharmacy Pick-Up” and follow the prompts if you prefer in-store pickup instead of home delivery.

When can I choose Walmart pickup for Zepbound Vials?

Starting mid-November, Walmart pickup will be available for Zepbound vials ordered through LillyDirect powered by Gifthealth pharmacy.

How does payment work for Walmart Pickup?

Patients can pay directly at the Walmart Pharmacy counter when picking up their medication. Pricing remains consistent whether you select home delivery or pickup. Pickup also allows for cash or in-store payment options.

Which local pharmacy locations are available for prescription pickup?

We’re partnering with Walmart Pharmacy locations across the U.S. During checkout, select “Local Pharmacy Pick-Up”, enter your ZIP code, and choose your preferred location.

Can I switch from home delivery to Walmart pickup after placing my order?

We understand plans change!

However, pickup options—such as home delivery or Walmart pickup—must be selected during checkout. Once your order is placed, the delivery method can’t be changed. If you’ve changed your mind and would like to switch back to home delivery, you can either call GiftHealth at 1-833-707-6619 or speak directly with the pharmacist at Walmart.

If I start with Walmart pickup, can I go back to Gifthealth delivery later?

Absolutely! After your order is placed, if you decide to switch to home delivery, call Gifthealth at 1-833-707-6619 or talk to your Walmart pharmacist to make the change.

Can I move back and forth between Walmart pickup and Gifthealth delivery for future orders?

Yes! You can switch between Walmart pickup and Gifthealth home delivery each month as needed. You’re free to switch it up from month to month.

How will I know when my prescription is ready for pickup at Walmart?

You’ll receive a text, email, or phone call from Walmart Pharmacy when your prescription is ready, so you’ll know exactly when to go!

How long will it take for my prescription to be ready at Walmart? Is it faster than Gifthealth?

Transfer to Walmart: 1–2 business days

Preparation at Walmart: 1–2 business days

Your Zepbound vials should be ready within 1–4 business days through Walmart.

LillyDirect powered by Gifthealth aims for prompt delivery, within 1-3 business day of your order being placed.

Where is my prescription? I selected Walmart, but they said they do not have it.

If Walmart says they don’t have it yet, it may still be in transit or processing. Call Gifthealth at 1-833-707-6619 to confirm or request a transfer.

I could only transfer one dose — how do I transfer the rest?

Contact Gifthealth at 1-833-707-6619 to transfer additional doses of your Zepbound vial prescriptions.

Where should I send my prescription if I want Walmart pickup?

Continue sending prescriptions to LillyDirect Self-pay Pharmacy. Patients can then choose Walmart pickup during checkout.

I picked the wrong Walmart location — what now?

Patients can request a transfer to a different Walmart location by speaking directly with their Walmart pharmacist.

I heard patients can get the Zepbound vials for self-pay at Walmart — is that true?

Yes! This collaboration gives patients more choice and access, combining discounted pricing with in-person support.

Why did LillyDirect choose Walmart for this collaboration?

Because of Walmart’s nationwide reach, trusted reputation, and commitment to accessible care.

With Walmart stores, this partnership helps expand access and simplify treatment for patients where they already shop.

Will Walmart pickup also be available at Sam’s Club locations?

Not at this time. Retail pickup for Zepbound (self-pay) is available only at Walmart Pharmacy locations.

Can I use my voucher for the Zepbound vial at Walmart?

Not at this time. Vouchers can only be used through home delivery.

When ordering medication through Ro, or other Lilly telehealth partners, is retail pickup available at checkout, or is home delivery the only option?

Currently, retail pickup is only available for LillyDirect Self-pay Pharmacy services. Other telehealth platforms only offer home delivery.

Insurance & CVS Coverage Changes

On July 1, 2025, Zepbound was removed from preferred coverage on some CVS Caremark plans.

Starting July 1, 2025, Zepbound was removed from preferred coverage on some plans.

Am I impacted?

Call CVS Caremark using the number on your insurance card and ask:

  • Am I on a plan affected by this change?
  • Are temporary overrides available?

What if my refill was denied?

It may be due to this coverage update. Contact your insurer and visit zepbound.lilly.com/access for help.

Prescriber Questions

How do I prescribe Zepbound vials?

To prescribe Zepbound vials through the LillyDirect Self Pay Pharmacy Solutions program:

Visit www.lillydirect.lilly.com/hcp for complete prescribing details and to guide your patients through the process.

What if I can’t find the vial option in your e-prescribing system?

If “Zepbound Vial” doesn’t appear, try the following:

  • Select the auto-injector option in your system.
  • In the notes or directions section, clearly write:
    “Vial/Inject one vial weekly,” along with the dose strength, quantity, and frequency of administration.
  • Please make sure to add the patient’s mobile phone number.

What happens after my prescription is submitted?

Your patient will receive a text message immediately once the prescription is received. They’ll be able to complete the checkout within 48 hours.

What if there’s an issue with my prescription?

If a prescription cannot be processed, you will receive a fax directly outlining the issue and what needs to be corrected.

Additional Info

Higher Zepbound Dose Availability.

  • The 12.5mg and 15mg Zepbound vial doses are now fully available for prescribers to order through the LillyDirect Self Pay program.
  • You’ll receive a text when your prescription is ready to order.

Medication Label FAQs

Your label may say “2ml (4 vials)” because each vial contains 0.5ml. Four vials = 2ml total. This is standard pharmacy labeling.

Eco-Friendly Packaging Tips

  • Reuse EPS foam coolers for picnics, beach days, or travel.
  • Recycle cardboard boxes curbside after removing gel packs and tape.
  • Gel packs and bubble wrap can be reused or disposed of responsibly.

Vial vs. Auto-Injector Transfers

Zepbound vials cannot be transferred to local pharmacies. If you want the auto-injector, you’ll need a new prescription from your provider.

Payment Link & Verification Issues

  • Double-check your name, date of birth, and phone number.
  • Ensure your phone accepts unknown calls or texts.
  • Try a secondary number if needed (e.g., home or spouse’s phone).
  • Still stuck? Contact us for help verifying your prescription